2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0806AS1
    Proguanil-d6 hydrochloride
    		Inhibitor 98.73%
    Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.
    Proguanil-d6 hydrochloride
  • HY-N7489
    β-Hederin
    		Inhibitor
    β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively.
    β-Hederin
  • HY-66005S4
    Acetaminophen-13C2,15N
    		98.30%
    Acetaminophen-13C2,15N is the 13C and 15N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].
    Acetaminophen-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-12785S
    Albendazole sulfoxide-d3
    		Inhibitor 99.79%
    Albendazole sulfoxide-d3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.
    Albendazole sulfoxide-d<sub>3</sub>
  • HY-W049875
    Nitroxynil
    		Inhibitor 98.71%
    Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica.
    Nitroxynil
  • HY-B0318S2
    Metronidazole-d3
    		Inhibitor ≥99.0%
    Metronidazole-d3 is deuterium labeled Metronidazole.
    Metronidazole-d<sub>3</sub>
  • HY-N9320
    13,21-Dihydroeurycomanone
    		Inhibitor 98.11%
    13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii.
    13,21-Dihydroeurycomanone
  • HY-U00295
    Melarsonyl
    		Inhibitor
    Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl
  • HY-153021
    NMT-IN-1
    		Inhibitor ≥98.0%
    NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis.
    NMT-IN-1
  • HY-B1244S
    Dimetridazole-d3
    		Inhibitor 99.87%
    Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
    Dimetridazole-d<sub>3</sub>
  • HY-121002
    Alstonine
    		Inhibitor
    Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties.
    Alstonine
  • HY-B0744C
    L-Eflornithine
    L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1.
    L-Eflornithine
  • HY-117025
    Manzamine A
    		Inhibitor
    Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1.
    Manzamine A
  • HY-N10534
    Lewis X trisaccharide
    		Inhibitor ≥99.0%
    Lewis X trisaccharide (Lewis X, Lex) is a potent TH2 regulator, antagonizes LPS-induced IL-12 immune expression. Lewis X trisaccharide is a human histo-blood group antigen, plays an key role in cell-cell adhesion, and servers as a tumor marker. Lewis X trisaccharide is highly expressed in the outer membrane of the parasite, can be used for the immunology research of schistosomiasis.
    Lewis X trisaccharide
  • HY-B2186
    Piperazine adipate
    		Inhibitor ≥98.0%
    Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
    Piperazine adipate
  • HY-121495
    BKI-1369
    		Inhibitor 98.77%
    BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves.
    BKI-1369
  • HY-B0357S
    Diclazuril-d4
    		Inhibitor ≥98.0%
    Diclazuril-d4 is deuterium labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al[1][2].
    Diclazuril-d<sub>4</sub>
  • HY-107771
    Fluensulfone
    		Inhibitor 99.31%
    Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.
    Fluensulfone
  • HY-N8471
    Niazinin
    		Inhibitor 99.94%
    Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity.
    Niazinin
  • HY-109077
    Tigolaner
    		98.53%
    Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent.
    Tigolaner
Parasite Isoform Comparison

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